As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 3764-01-0, name is 2,4,6-Trichloropyrimidine, molecular formula is C4HCl3N2, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below. HPLC of Formula: C4HCl3N2
After 2,4,6-nichluropyiimidin 25g(l 362mm 1), phenylbu x n c acid 36.5g(299.3mmol), and tetrakis(triphenyLphosp}tine)palladium (1.118 Q96mmoL) were dissolved in toluene (408mL), 2.OM Na,CA, aqueous solution (204 mL) and ethanol (204mL) were added thereto. The mixture was stored under influx for 2 hours at 120C. Upon completion of the reaction, extraction with EA and purification by column chromatography gave a compound 1-2 (25g, 93.7mmol, 69%).
With the rapid development of chemical substances, we look forward to future research findings about 3764-01-0.
Reference:
Patent; ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD.; LEE, Hyo Jung; CHO, Young Jun; KWON, Hyuck Joo; KIM, Bong Ok; KIM, Sung Min; WO2011/71255; (2011); A1;,
Pyrimidine | C4H4N2 – PubChem,
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