The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 34289-60-6, name is 4,6-Dimethylpyrimidin-2-ol hydrochloride. This compound has unique chemical properties. The synthetic route is as follows. Safety of 4,6-Dimethylpyrimidin-2-ol hydrochloride
Add 160 mg (1 mmol) to a 100 mL eggplant bottle 2-hydroxy-4,6-dimethylpyrimidine hydrochloride, 318 mg (3 mmol) benzaldehyde and 0.1 mL (1.2 mmol) concentrated hydrochloric acid,Anhydrous ethanol (40 mL) was added to dissolve the reaction, and the mixture was heated under reflux at 80 C for 24h.After the reaction is completed, the solvent is distilled off under reduced pressure.Add a saturated sodium bicarbonate aqueous solution and stir to remove the acid.The crude product was washed with water and dried and purified by column chromatography (methanol: dichloromethane = 1:10).0.21 g of 2-hydroxy-4,6-distyrylpyrimidine was obtained in a yield of 70%.
With the rapid development of chemical substances, we look forward to future research findings about 34289-60-6.
Reference:
Patent; Ocean University of China; Jiang Tao; Zhang Lijuan; Tong Sheng; Zhang Meng; (30 pag.)CN105198820; (2019); B;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia