Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 50270-27-4, name is 2,4,6-Trichloropyrimidine-5-carbaldehyde. A new synthetic method of this compound is introduced below., HPLC of Formula: C5HCl3N2O
Step 3: To a solution of 7f (1.5g, 7.1mmol) in EtOH (50mL) was added drop-wise a solution of 7e (6.8g, 20mmol) in EtOH (30mL), followed by TEA (4.46mL, 32mmol) at -78°C. The resulting mixture was stirred at -78°C for 30min, warmed to 0°C for 30min and adjusted to pH=5~6 with 3N HCl subsequently. The solid was collected by filtration, washed with water and cold ethanol and dried to give 7g (1.04g, 60percent).
If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 50270-27-4, 2,4,6-Trichloropyrimidine-5-carbaldehyde.
Reference:
Patent; TYROGENEX, INC.; LIANG, Congxin; WO2011/41399; (2011); A2;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia