Electric Literature of 50593-92-5, Adding some certain compound to certain chemical reactions, such as: 50593-92-5, name is 5-Bromo-2-(methylthio)pyrimidine-4-carboxylic acid,molecular formula is C6H5BrN2O2S, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 50593-92-5.
(b). 2-Methylsulfanyl-pyrimidine-4-carboxylic acid; The product of example 21a (517 mg) in methanol (25 ml) was hydrogenated in a PARR apparatus in the presence of KOH (260 mg) and 10% Pd on BaSO4 (260 mg) for4 h. The reaction mixture was filtered over decalite and washed with methanol (warm), The filtrate was concentrated to 50% of its volume followed by addition of cone. HCl(33%) to pH 1. The precipitate (KBr) was filtered off and the mother liquor was concentrated in vacuo. The residue was recrystallized from dioxane. Yield: 200 mg. MS-ESI: [M+H]+ = 170
According to the analysis of related databases, 50593-92-5, the application of this compound in the production field has become more and more popular.
Reference:
Patent; N.V. ORGANON; WO2006/117368; (2006); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia