Reference of 58536-46-2, Adding some certain compound to certain chemical reactions, such as: 58536-46-2, name is 4-(4-Bromophenyl)-2,6-diphenylpyrimidine,molecular formula is C22H15BrN2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 58536-46-2.
General procedure: A mixture of 4-(4-bromophenyl)-2,6-diphenylpyrimidine (4.06 g, 10.5 mmol), compoundBFCz (2.57 g, 10 mmol), CuI (0.19 g, 1 mmol), K2CO3 (6.9 g, 50 mmol),18-crown-6 (0.264 g, 1 mmol) were dissolved in 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone (DMPU 10 mL) and stirred at 180 Cunder a nitrogen atmosphere for 48 h. After cooling to room temperature,the mixture was extracted with CH2Cl2 and water. The organicphase was dried over anhydrous MgSO4 and filtered. After removal ofthe solvent, the residue was purified by column silica gel chromatography(PE: DCM=10:1) and recrystallized to afford a white productin 64% yield (3.6 g).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 58536-46-2, 4-(4-Bromophenyl)-2,6-diphenylpyrimidine, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Zhang, Qing; Xiang, Songpo; Huang, Zhi; Sun, Shuaiqiang; Ye, Shaofeng; Lv, Xialei; Liu, Wei; Guo, Runda; Wang, Lei; Dyes and Pigments; vol. 155; (2018); p. 51 – 58;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia