Sireesha, Reddymasu et al. published their research in Polycyclic Aromatic Compounds | CAS: 90905-32-1

2-Methoxypyrimidine-5-carbaldehyde (cas: 90905-32-1) belongs to pyrimidine derivatives. The aromatic compound pyrimidine, and its derivatives, are ubiquitous in nature. They are found in nucleic acids, vitamins, amino acids, antibiotics, alkaloids, and a variety of toxins. Drugs having the pyrimidine motif have manifested to exhibit gratifying biological activity like anticancer, antiviral, anti-inflammatory, antibacterial, and antihypertensive activities.HPLC of Formula: 90905-32-1

Synthesis of Substituted Aryl Incorporated Oxazolo[4,5-b]Pyridine-Triazole Derivatives: Anticancer Evaluation and Molecular Docking Studies was written by Sireesha, Reddymasu;Tej, Mandava Bhuvan;Poojith, Nuthalapati;Sreenivasulu, Reddymasu;Musuluri, Murali;Subbarao, Mannam. And the article was included in Polycyclic Aromatic Compounds.HPLC of Formula: 90905-32-1 This article mentions the following:

A new series of structurally modified oxazolo[4,5-b]pyridine based triazoles derivatives I (R = 4-Me, 4-Cl, 4-CN, etc.) were synthesized, and designed and screened for their anticancer activities against human cancer cell lines like PC3 (prostate), A549 (lung), MCF-7 (breast), and DU-145 (prostate) by using MTT assay method. Most of the tested compounds exhibited good to moderate anticancer potential in comparison with etoposide. Among all, compounds I (R = 3,4,5-(OMe)3, 3,5-(OMe)2, 4-MeO, 4-Me, 4-NMe2, 3,5-(NO2)2) displayed promising anticancer activities on four cell lines. Furthermore, mol. docking studies were carried out on human dihydroorotate dehydrogenase (hDHODH), a potential target for anticancer drugs, that is linked to proliferation, invasion, and migration of cancerous cell in acute myeloid leukemia, colorectal cancer melanoma, and pancreatic cancer cells. The investigated oxazolo[4,5-b]pyridine-based triazoles showed efficient inhibition of hDHODH in mol. docking studies. In the experiment, the researchers used many compounds, for example, 2-Methoxypyrimidine-5-carbaldehyde (cas: 90905-32-1HPLC of Formula: 90905-32-1).

2-Methoxypyrimidine-5-carbaldehyde (cas: 90905-32-1) belongs to pyrimidine derivatives. The aromatic compound pyrimidine, and its derivatives, are ubiquitous in nature. They are found in nucleic acids, vitamins, amino acids, antibiotics, alkaloids, and a variety of toxins. Drugs having the pyrimidine motif have manifested to exhibit gratifying biological activity like anticancer, antiviral, anti-inflammatory, antibacterial, and antihypertensive activities.HPLC of Formula: 90905-32-1

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia