The pyrimidine ring system has wide occurrence in nature as substituted and ring fused compounds and derivatives, including the nucleotides cytosine, thymine and uracil, thiamine (vitamin B1) and alloxan. 109-12-6, formula is C4H5N3, Name is Pyrimidin-2-amine. It is also found in many synthetic compounds such as barbiturates and the HIV drug, zidovudine. Name: Pyrimidin-2-amine.
Slavchev, Ivaylo;Ward, Jas. S.;Rissanen, Kari;Dobrikov, Georgi M.;Simeonov, Svilen research published 《 Base-promoted direct amidation of esters: beyond the current scope and practical applications》, the research content is summarized as follows. The base-promoted direct amidation of unactivated esters is among the most useful reactions for amide bond formation in contemporary organic chem. The intensive research in this area has led to the development of a number of new methods to achive this transformation. However, to date, the existing literature is more methodol. and in many instances lacks practical directions. Therefore, the full potential of this transformation is yet to be revealed by broadening the substrate scope. In a search for new practical applications of the amidation reaction, herein a comprehensive study of a number of base-promoted direct amidations that encompass a wide range of amines and esters is presented. Furthermore, authors applied their findings in the synthesis of phosphoramidates and several industrially relevant products.
109-12-6, 2-Aminopyrimidine is a useful research compound. Its molecular formula is C4H5N3 and its molecular weight is 95.1 g/mol. The purity is usually 95%.
2-Aminopyrimidine is an organic compound that belongs to the group of pyridines. It has been shown to have antimicrobial, antitumor, and antiviral properties. 2-Aminopyrimidine has been used as a fungicide and herbicide in horticulture and agriculture, respectively. The molecular geometry of this molecule is octahedral with coordination geometry C2v. This chemical binds to the BCR-ABL kinase receptor and inhibits its activity by competitive inhibition of ATP binding. 2-Aminopyrimidine has been shown to have a hematologic response in vivo models and in vitro assays. It also has anti-inflammatory effects when it is taken orally or applied topically., Name: Pyrimidin-2-amine
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia