Solberg, Jan’s team published research in Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry in 1986-05-31 | 99469-85-9

Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry published new progress about Coupling reaction. 99469-85-9 belongs to class pyrimidines, and the molecular formula is C5H4Cl2N2S, Related Products of 99469-85-9.

Solberg, Jan; Undheim, Kjell published the artcile< Palladium catalysis in the preparation of alkynylpyrimidines>, Related Products of 99469-85-9, the main research area is iodopyrimidine alkyne coupling; palladium complex catalyst coupling; alkynylpyrimidine; pyrimidine alkynyl.

Coupling reaction of iodopyrimidines I (R = SMe, OSiMe3; R1 = iodo) with R2CCH (e.g., R2 = Ph, Bu) using Pd catalysts gave alkynylpyrimidines I (R1 = CCR2). Hydrolysis of I (R = OSiMe3, R1 = CCR2) with H2O at room temperature gave pyrimidinones II. m-ClC6H4C(O)OOH oxidn of I (R = SMe, R1 = CCR2) gave I (R = SO2Me). I (R = SO2Me, R1 = CCPh) on alk. hydrolysis gave II (R2 = Ph).

Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry published new progress about Coupling reaction. 99469-85-9 belongs to class pyrimidines, and the molecular formula is C5H4Cl2N2S, Related Products of 99469-85-9.

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia