Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 148-51-6, is researched, Molecular C8H12ClNO2, about Preconvulsive changes in brain glucose metabolism following drugs inhibiting glutamate decarboxylase, the main research direction is convulsant brain glucose glycogen; allylglycine brain glucose glycogen; deoxypyridoxine brain glucose glycogen; methionine sulfoximine brain glucose; isoniazid brain glucose glycogen; temperature brain glucose convulsant.Formula: C8H12ClNO2.
DL-C-allylglycine (I) [7685-44-1], 4-deoxypyridoxine-HCl (II) [148-51-6], and DL-methionine-D-sulfoximine (III) (180, 250, and 300 mg/kg resp., i.p.) each induced preconvulsive increases in the brain glucose [50-99-7] concentration of mice at room temperature; II and III also increased brain glycogen [9005-79-2] concentrations in room-temperature mice, but only II did so in mice maintained at 33-4°. Only with I was the increase in brain glucose concentration associated with an increase in blood glucose concentration I, II, III, or isoniazid [54-85-3] (150 mg/kg) reduced rectal temperature in mice at room temperature but not those at 33-4°. Isoniazid reduced brain glucose and glycogen concentrations in mice at 33-4°, but did not affect mice at room temperature The relation between the effects of these drugs on brain carbohydrates and amino acid metabolism is discussed.
As far as I know, this compound(148-51-6)Formula: C8H12ClNO2 can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.
Reference:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia