Adding a certain compound to certain chemical reactions, such as: 19875-05-9, 4,6-Dichloro-2-(chloromethyl)pyrimidine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, COA of Formula: C5H3Cl3N2, blongs to pyrimidines compound. COA of Formula: C5H3Cl3N2
Description 128; 4, 6-Dichloro-2-iodomethylpyrimidine; A mixture of 4, 6-dichloro-2-chloromethylpyrimidine [Annales Pharmaceutici (Poznan) 12, 33-38, 1977] (3.3 g, 16.7 mmol) and sodium iodide (3.25 g, 21.7 mmol) in acetone (70 ml) was stirred at room temperature for 3 hours. The reaction mixture was concentrated to dryness. The residue was dissolved in ethyl acetate and the organic solution was washed with sodium thiosulfate solution (aq), brine, dried over sodium sulfate, filtered and concentrated to give a brown solid (4.5 g, 93 %). IH NMR (360 MHz, DMSO-d6) 4.53 (2 H, s), 7.93 (1 H, s).
The synthetic route of 19875-05-9 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; MERCK SHARP & DOHME LIMITED; WO2005/47279; (2005); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia