Some scientific research about 2915-16-4

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,2915-16-4, its application will become more common.

Synthetic Route of 2915-16-4, In the chemical reaction process,reaction time,type of solvent,can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product.An updated downstream synthesis route of 2915-16-4 as follows.

Example 90; [4- (4, 6-Diphenylpyrimidin-2-yl) -phenyl]methanol; A mixture of 2-chloro-4, 6-diphenylpryimidine, 0.79g (2.96 mmol), 4- (hydroxylmethyl)phenylboronic acid, 0.45g (2.96 mmol), Pd (PPh3) 4, 342mg (0.296 mmol), in 2 mL of toluene and EPO ImL of methanol was heated to obtain a clear solution. To the solution was added 2mL of 4.0M aq. Na2CO3. The reaction mixture refluxed for lbetah at 70 C. The mixture was cooled to room temperature and diluted with 10OmL ethyl acetate. The organic layer was washed with water, sat. aq. NaCl, and dried (MgSO4) . After the solution was concentrated, the residue was recrystallized with Et2O-Heptane (1:1) to afford the desired product in 0.38g (38%) as a yellow solid.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,2915-16-4, its application will become more common.

Reference:
Patent; THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC; WO2006/55725; (2006); A2;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia