The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. HPLC of Formula: C4H4ClN3, 3993-78-0, Name is 2-Amino-4-chloropyrimidine, SMILES is C1=CN=C(N=C1Cl)N, in an article , author is Balasubramaniam, Arun, once mentioned of 3993-78-0.
Repurposing INCI-registered compounds as skin prebiotics for probiotic Staphylococcus epidermidis against UV-B
Repurposing existing compounds for new indications may facilitate the discovery of skin prebiotics which have not been well defined. Four compounds that have been registered by the International Nomenclature of Cosmetic Ingredients (INCI) were included to study their abilities to induce the fermentation of Staphylococcusepidermidis (S. epidermidis), a bacterial species abundant in the human skin. Liquid coco-caprylate/caprate (LCC), originally used as an emollient, effectively initiated the fermentation of S. epidermidis ATCC 12228, produced short-chain fatty acids (SCFAs), and provoked robust electricity. Application of LCC plus electrogenic S. epidermidis ATCC 12228 on mouse skin significantly reduced ultraviolet B (UV-B)-induced injuries which were evaluated by the formation of 4-hydroxynonenal (4-HNE), cyclobutane pyrimidine dimers (CPD), and skin lesions. A S. epidermidis S2 isolate with low expressions of genes encoding pyruvate dehydrogenase (pdh), and phosphate acetyltransferase (pta) was found to be poorly electrogenic. The protective action of electrogenic S. epidermidis against UV-B-induced skin injuries was considerably suppressed when mouse skin was applied with LCC in combination with a poorly electrogenic S. epidermidis S2 isolate. Exploring new indication of LCC for promoting S. epidermidis against UV-B provided an example of repurposing INCI-registered compounds as skin prebiotics.
But sometimes, even after several years of basic chemistry education, it is not easy to form a clear picture on how they govern reactivity! 3993-78-0, you can contact me at any time and look forward to more communication. HPLC of Formula: C4H4ClN3.
Reference:
Pyrimidine | C4H4N2 – PubChem,
,Pyrimidine – Wikipedia