Synthetic Route of 180869-38-9, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.180869-38-9, name is 4-(Dimethoxymethyl)-N-methylpyrimidin-2-amine, molecular formula is C8H13N3O2, molecular weight is 183.21, as common compound, the synthetic route is as follows.
Aqueous 4 M HCI (2 ml) was added to a solution of 4-(dimethoxymethyl)-A/- methylpyrimidin-2-amine (0.060 g, 0.33 mmol) in THF (1 ml). The resulting mixture was heated to 40 C overnight and then cooled to room temperature. The reaction mixture containing the hydrochloride salt of the aldehyde was used directly in the next step without isolation.
The chemical industry reduces the impact on the environment during synthesis 180869-38-9, I believe this compound will play a more active role in future production and life.
Reference:
Patent; THE UNIVERSITY OF MELBOURNE; WILLIAMS, Spencer; SHAH, Sayali; HAKKI, Zalihe; STEWART, Alastair; (154 pag.)WO2018/201192; (2018); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia