Related Products of 115617-41-9, In the chemical reaction process,reaction time,type of solvent,can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product.An updated downstream synthesis route of 115617-41-9 as follows.
(2) Synthesis of dl-5-chloro-6-ethyl-4-(alpha-methyl-4-methylthiobenzylamino)pyrimidine (Compound No. 62) 2 g (3.3 mmol) of 4,5-dichloro-6-ethylpyrimidine which is a material compound (IIc), 1.9 g (11 mmol) of dl-alpha-methyl-4-methylthiobenzylamine which is a material compound (IIId), 2 ml of triethylamine and a catalytic amount of 4-(N,N-dimethylamino)pyridine were dissolved in 10 ml of N,N-dimethylformamide and the solution was heated under reflux for 8 hours. After the reaction, extraction with toluene and washing with water were conducted, followed by drying over anhydrous sodium sulfate. The solvent was removed under reduced pressure and the resulting oily product was purified by silicagel column chromatography (Wako gel C-200, eluted with toluene:ethyl acetate = 4:1). The resultant was crystallized with hexane to give 1.8 g of the desired compound as colorless crystals (indicated in Table 19 as Compound No. 62).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,115617-41-9, its application will become more common.
Reference:
Patent; UBE INDUSTRIES, LTD.; EP424125; (1991); A2;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia