Related Products of 36314-97-3 ,Some common heterocyclic compound, 36314-97-3, molecular formula is C10H8ClN3, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
Compound 1e (13 g, 7.34 mmol) was dissolved in 300 mL of N,N-dimethylformamide and N-bromosuccinimide (12.38 g, 69.54 mmol) was added, and the reaction was stirred for 1 hour. The reaction was stopped, the reaction solution was poured into 1 L of water, stirred for 20 minutes, filtered, and the filter cake was dried.The crude title compound 2a (18 g) was obtained, which was used for the next step without purification.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,36314-97-3, its application will become more common.
Reference:
Patent; Jiangsu Hengrui Pharmaceutical Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd.; Lu Biao; Wang Shenglan; Shen Xiaodong; He Feng; Tao Weikang; (56 pag.)CN109535161; (2019); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia