Reference of 2915-16-4, Adding some certain compound to certain chemical reactions, such as: 2915-16-4, name is 2-Chloro-4,6-diphenylpyrimidine,molecular formula is C16H11ClN2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 2915-16-4.
Inthe nitrogen ambient, after the compound 1-3 20 g (46.5 mmol) was melted in thetetrakis tetrahydrofuran (THF) 0.2 L here 2- chloro- 4,6- diphenylpyrimidine (2-chloro-4,6-diphenylpyrimidine)12.4 g (46.5 mmol) and tetrakis (triphenylphosphine) palladium(tetrakis(triphenylphosphine)palladium) 0.54 g (0.47 mmol) were put and itmixed. The saturated potassium carbonate 16.1 g (116 mmol) was put in water andit heated up in 80 for 15 hours and it refluxed.After water was put in into the reaction solution after the reaction completionand it extractedin the dichloromethane (DCM) moisture was removed to the anhydrous MgSO4 itfiltered and it was concentrated under reduced pressure. The residue obtainedin this way was refined to the flash column chromatography after dividing andthe compound A -14 20.4 g (82 %) was obtained.
According to the analysis of related databases, 2915-16-4, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Cheil Industries Co., Ltd.; Oh, Jae Jin; Kang, Gi Wook; Kang, Uii Soo; Kim, Yun Hwan; Kim, Hun; Yang, Yong Tak; Yu, Uhn Sun; Lee, Nam Hun; Lee, Han Ir; Jo, Pyung Suk; (66 pag.)KR2015/28579; (2015); A;,
Pyrimidine | C4H4N2 – PubChem,
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