Reference of 1722-12-9, Adding some certain compound to certain chemical reactions, such as: 1722-12-9, name is 2-Chloropyrimidine,molecular formula is C4H3ClN2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 1722-12-9.
General procedure: To a 50 mL screw-capped thick-walled Pyrex tube equipped with a magnetic stirrer, 3-methylindole(1a, 131.0 mg, 1.0 mmol), 1,2-dichlorobenzene (2a, 365.0 mg, 2.5 mmol), KOH (168.2 mg, 3.0 mmol) and DMSO (5.0 mL) were added sequentially under a nitrogen atmosphere. The tube was then sealedand stirred at 100 C for 24 h. After removal of the solvent under reduced pressure, purification was performed by flash column chromatography on silica gel with petroleum ether/ethyl acetate (gradient mixture ratio from 100:0 to 90:10) as eluent to afford N-(2-chlorophenyl)-3-methylindole (3aa, 171.8 mg,0.71 mmol, 71% yield).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 1722-12-9, 2-Chloropyrimidine, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Iqbal, Muhammad Asif; Mehmood, Hina; Lv, Jiaying; Hua, Ruimao; Molecules; vol. 24; 6; (2019);,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia