Synthetic Route of 114040-06-1, In the chemical reaction process,reaction time,type of solvent,can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product.An updated downstream synthesis route of 114040-06-1 as follows.
EXAMPLE 13 3-Bromo-5,7-dimethoxypyrazolo(1,5-a)pyrimidine To a solution of 1.2 g of sodium dissolved in 60 ml of methanol was added 6.7 g of 3-bromo-5,7-dichloropyrazolo(1,5-a)pyrimidine. The resulting mixture was stirred at room temperature for 12 hours and was then concentrated under reduced pressure. The residue was then stirred in water and was then filtered. The solid collected was washed with ether and was dried in oven at 50 C. for 12 hours to give 5.24 g of the desired product, m.p. 188-190 C. NMR(CDCl3)delta: 4.05 (s, 3H); 4.14 (s, 3H); 5.7 (s, 1H); and 7.94 (s, 1H).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,114040-06-1, its application will become more common.
Reference:
Patent; E. I. Du Pont de Nemours and Company; US4838925; (1989); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia