Adding a certain compound to certain chemical reactions, such as: 3764-01-0, 2,4,6-Trichloropyrimidine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Formula: C4HCl3N2, blongs to pyrimidines compound. Formula: C4HCl3N2
To an ice-cold solution containing 2, 4, 6-trichloropyrimidine (8 g, 44 mmol) in MeOH (80 mL) and NAHCO3 (10 g) add slowly and dropwise a methanolic solution (20 mL) of morpholine (4 mL, 46 mmol). Allow the mixture to warm to 25C and stir overnight. Before diluting with water, vigorously stir for 1 hour, and filter to give white crystalline solid (10 g) as a mixture of regioisomers. Carefully recrystallize from toluene to give 6-morpholino-2, 4- dichloropyrimidine. Concentrate the mother liquor and carefully recrystallize from ETOH to give 4, 6-dichloro-2-morpholinopyrimidine.
The synthetic route of 3764-01-0 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; NEUROGEN CORPORATION; WO2005/7648; (2005); A2;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia