Synthetic Route of 39876-88-5, Adding some certain compound to certain chemical reactions, such as: 39876-88-5, name is 4-Chlorobenzofuro[3,2-d]pyrimidine,molecular formula is C10H5ClN2O, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 39876-88-5.
1-bromo-9H- carbazole (5.0 g, 20.3 mmol) and sodium hydride (1.4 g, 34.5 mmol) were mixed in 200 mL of dry DMF. The solution was stirred for 4 hours and the addition of 4-chlorobenzofuro[3,2-d]pyrimidine(7.9 g, 38.6 mmol). The mixture was refluxed under nitrogen overnight. The reaction mixture was placed in water and the precipitate was then filtered off. After the residue with eluent THF: hexane (1: 1, v / v) was purified by column chromatography using. Of the yellow product was collected 4 .1 g (49%).
According to the analysis of related databases, 39876-88-5, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Universal Display Corporation; Joseph, Scott; Kwang, Raymond; Lee, Chi Hang; Shia, Chuan Jun; Ram, SiV Cheung; (131 pag.)KR2015/9461; (2015); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia