Adding a certain compound to certain chemical reactions, such as: 5305-40-8, 4,6-Dichloropyrimidine-5-carbaldehyde, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Formula: C5H2Cl2N2O, blongs to pyrimidines compound. Formula: C5H2Cl2N2O
4,6-dichloropyrimidine-5-carbaldehyde (16.95 mmol, 3 g) was dissolved in 20 ml of toluene,Ammonia gas through 30min,Stirred overnight at room temperature,Filtration gave a yellow solid,Column chromatography (eluent ethyl acetate: petroleum ether = 1: 3)A white solid was obtained in 60% yield.
The synthetic route of 5305-40-8 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Shan Dong University; Zhao, Guisen; Lu, Jinjie; Wang, Guanjie; Yang, Dezhi; Zhang, Zhen; Jing, Yongkui; (32 pag.)CN106045918; (2016); A;,
Pyrimidine | C4H4N2 – PubChem,
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