Reference of 769-42-6, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 769-42-6, name is 1,3-Dimethylbarbituric acid, molecular formula is C6H8N2O3, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
General procedure: A mixture of 1.1 mmol aromatic aldehyde, 0.144 g 2 (1 mmol), 0.156 g 3 (1 mmol), and 0.01 g ZnO NPs (10 mol%) in a round bottom flask was heated in an oil bath at 110 C for 20-35 min. During the reflux the reaction was monitored by TLC (eluent: n-hexane: ethyl acetate, 1:1). After completion of the reaction the mixture was cooled to room temperature, then the reaction mixture was dissolved in dichloromethane and stirred for 5 min. The suspended solution was filtered and then heterogeneous nanocatalyst was recovered. Then solvent was evaporated and the solid was recrystallized from methanol to afford the pure product 4.
According to the analysis of related databases, 769-42-6, the application of this compound in the production field has become more and more popular.
Reference:
Article; Mohaqeq, Mahboubeh; Safaei-Ghomi, Javad; Monatshefte fur Chemie; vol. 146; 9; (2015); p. 1581 – 1586;,
Pyrimidine | C4H4N2 – PubChem,
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