Application of 696-82-2 ,Some common heterocyclic compound, 696-82-2, molecular formula is C4HF3N2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
(1) adding 100% of a 2,4-diaminobenzenesulfonic acid solution (18.8 g) to 400 mL of water, stirring Add sodium bicarbonate solid, adjust the pH to 4, slowly warm to 20 C after dissolution, add 13.94 g (99%) 2,4,6-trifluoropyrimidine, control the pH at 4, continue the reaction 2 Hours, the end point of the reaction was detected by thin layer chromatography, and the reaction solution was used after the condensation was completed;
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,696-82-2, its application will become more common.
Reference:
Patent; Jiangsu Demeike Chemical Co., Ltd.; Wang Siliang; Wang Xiaojun; (16 pag.)CN108129875; (2018); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia