Adding a certain compound to certain chemical reactions, such as: 4318-56-3, 6-Chloro-3-methylpyrimidine-2,4(1H,3H)-dione, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, name: 6-Chloro-3-methylpyrimidine-2,4(1H,3H)-dione, blongs to pyrimidines compound. name: 6-Chloro-3-methylpyrimidine-2,4(1H,3H)-dione
In toluene was added with stirring 506.77 g of methyl-6-chloro-uracil 96.36 g, 2-cyanobenzylbromide 129.36 g, triethylamine 45.54 g, the reaction was stirred for about 80 C, cooled to room temperature, purified water was added with stirring analysis crystal suction filtration and dried to afford the product 146.62 g, mp: 164.6-166.5 C
At the same time, in my other blogs, there are other synthetic methods of this type of compound,4318-56-3, 6-Chloro-3-methylpyrimidine-2,4(1H,3H)-dione, and friends who are interested can also refer to it.
Reference:
Patent; Jilin Pharmaceutical College; Chang Sheng; Ma Jingjie; Zheng Xianjing; Dong Linlin; Yin Shuzhu; (10 pag.)CN108912093; (2018); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia