Adding a certain compound to certain chemical reactions, such as: 29274-24-6, 5-Chloropyrazolo[1,5-a]pyrimidine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Recommanded Product: 5-Chloropyrazolo[1,5-a]pyrimidine, blongs to pyrimidines compound. Recommanded Product: 5-Chloropyrazolo[1,5-a]pyrimidine
Add 5-chloropyrazolo [1,5-a] pyrimidine (19.6mmol), (2,5-difluorophenyl) methylamine (19.6mmol), and anhydrous n-butanol ( 15 mL) and N, N-diisopropylethylamine (DIPEA 55 mmol).The pale yellow suspension was sealed and heated in an oil bath (160 C) overnight.The reaction was cooled to ambient temperature, transferred to a 100 ml pear-shaped bottle, and concentrated under reduced pressure to remove as much as possible n-butanol and N, N-diisopropylethylamine (DIPEA) to obtain a crude yellow oil. Ether: acetone = 5: 1) to give a pale yellow solid.
The synthetic route of 29274-24-6 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Jin Qiu; (36 pag.)CN110734437; (2020); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia