Related Products of 56826-69-8, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 56826-69-8 as follows.
A 150 mL toluene solution of 5,6,7-trihydroquinolin-8-one (0.882 g, 5.99 mmol), 2-benzhydrylnaphthylamine (2.04 g, 6.59 mmol), and a catalytic amount of p-toluenesulfonic acid (0.228 g, 1.20 mmol) was refluxed for 8 h. The solvent was evaporated under reduced pressure, and then the mixture was purified by column chromatography on basic alumina with petroleum ether/ethyl acetate (v/v = 10:1) as eluent to afford the product as a yellow powder in 37% yield. Mp: 165-166 C. 1H NMR (400 MHz, CDCl3, TMS): deltaH 8.80 (d, 1H, 3JHH = 3.2 Hz, Py-H), 7.79 (d, 1H, 3JHH = 8.0 Hz, Py-H), 7.57 (d, 1H, 3JHH = 8.4 Hz, Py-H), 7.50 (d, 2H, 3JHH = 8.4 Hz, Ar-H), 7.41-7.08 (m, 14H, Ar-H), 5.92 (s, 1H, -CHPh2), 2.72-2.64 (m, 1H, -CH2), 2.53-2.46 (m, 1H, -CH2), 1.90-1.83 (m, 1H, -CH2), 1.20-1.13 (m, 1H, -CH2), 0.88-0.77 (m, 2H, -CH2). 13C NMR (100 MHz, CDCl3, TMS): 167.8, 149.8, 148.9, 146.2, 144.5, 142.9, 137.5, 137.2, 132.8, 130.2, 129.7, 128.6, 128.3, 128.1, 127.6, 126.1, 125.5, 125.0, 123.5, 122.5, 51.8, 31.4, 29.2, 21.2. FT-IR (KBr, disk, cm-1): 3054, 3026, 1641 (nuC=N), 1564, 1488, 1450, 1428, 1375, 1315, 1199, 1097, 1028, 790, 745, 701. Anal. Calc.d for C32H26N2 (438.21): C, 87.64; H, 5.98; N, 6.39%; Found: C, 87.48; H, 6.22; N, 6.27%.
According to the analysis of related databases, 56826-69-8, the application of this compound in the production field has become more and more popular.