Adding a certain compound to certain chemical reactions, such as: 6328-58-1, 6-Methyl-2-(methylthio)-1H-pyrimidin-4-one, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 6328-58-1, blongs to pyrimidines compound. Recommanded Product: 6-Methyl-2-(methylthio)-1H-pyrimidin-4-one
A mixture of 0.01 mol of 6-methyl-2-(methylsulfanyl)-pyrimidin-4(3H)-one and 0.02 mol of pyrrolidine in 20 mL of butan-1-ol was heated for 15 h at 130140C. The solvent was distilled off, the residue was treated with diethyl ether, and the precipitate was ltered off and dried. Yield 72%, mp 240242C. IR spectrum: nu 1646 cm -1 (C=O). 1 H NMR spectrum, delta, ppm: 1.921.99 m (4H, CH 2 CH 2 ), 2.04 s (3H, CH 3 ), 3.433.51 m (4H, CH 2 NCH 2 ), 5.32 s (1H, 5-H), 10.84 br.s (1H, OH). 13 C NMR spectrum, delta C , ppm: 23.7, 24.7, 46.1, 98.8, 152.2, 163.7, 165.1. Found, %: C 60.21; H 7.26; N 23.20. C 9 H 13 N 3 O. Calculated, %: C 60.32; H 7.31; N 23.45.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,6328-58-1, its application will become more common.
Reference:
Article; Pivazyan; Ghazaryan; Azaryan, Zh. A.; Yengoyan; Russian Journal of General Chemistry; vol. 89; 10; (2019); p. 2010 – 2017; Zh. Obshch. Khim.; vol. 89; 10; (2019); p. 1511 – 1519,9;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia