Adding a certain compound to certain chemical reactions, such as: 63155-11-3, Ethyl 2-(pyrimidin-2-yl)acetate, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, name: Ethyl 2-(pyrimidin-2-yl)acetate, blongs to pyrimidines compound. name: Ethyl 2-(pyrimidin-2-yl)acetate
To a solution of ethyl 2-(pyrimidin-2-yl)acetate (Example 31b, 410 mg, 2.47 mmol)in ethanol (5 mL) was added 2N NaOH (2 mL) at room temperature under nitrogen. Thereaction mixture was stirred at room temperature under nitrogen for 72 hours, then5 concentrated under reduced pressure. The residue was triturated with ethanol andconcentrated under reduced pressure to give the title compound, which was carried onto thenext step without further purification. MS 139 (MH+).
The synthetic route of 63155-11-3 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; SENOMYX, INC.; TACHDJIAN, Catherine; KARANEWSKY, Donald; WERNER, Sara; DARMOHUSODO, Vincent; YAMAMOTO, Jeff; WO2014/25706; (2014); A1;,
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