Adding a certain compound to certain chemical reactions, such as: 873-83-6, 6-Aminopyrimidine-2,4(1H,3H)-dione, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Formula: C4H5N3O2, blongs to pyrimidines compound. Formula: C4H5N3O2
General procedure: A mixture of isatin (0.147 g, 1 mmol), acetophenone (0.09 mL, 1.5 mmol), and piperidine (two drops, 0.1 mmol) in ethanol (95.5percent, 1 mL) was heated at 80 ¡ãC for about 5 min. To the solid obtained at this stage was added 6-amino-1,3-dimethyluracil (0.155 g, 1 mmol), p-toluenesulfonic acid monohydrate (0.076 g, 0.04 mmol), and EtOH (95.5percent, 2 mL). The mixture was stirred and heated gently at 80 ¡ãC. After completion of the reaction (115 min), as monitored by TLC using 5:1 ratio of ethyl acetate/n-hexane, the reaction mixture was cooled to room temperature and then filtered. The separated solids were washed twice with 10 mL of water and 3 mL of hot ethanol (95.5percent) to obtain the pure product 4a.
The synthetic route of 873-83-6 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Rad-Moghadam, Kurosh; Azimi, Seyyedeh Cobra; Tetrahedron; vol. 68; 47; (2012); p. 9706 – 9712;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia