The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 89284-85-5, name is Methyl 2,5,6-trichloropyrimidine-4-carboxylate. This compound has unique chemical properties. The synthetic route is as follows. Recommanded Product: 89284-85-5
Aqueous ammonia (30% solution; 8.0 ml, 0.42 mol) was added dropwise to a stirred solution of 6-methoxycarbonyl-2,4,5-trichloropyrimidine (20.0 g, 0.083 mol) in THF (1000 ml) at 0 0C. The reaction mixture was stirred at 0 C for 1 hour and then filtered. The filtrate was evaporated under reduced pressure to give a white solid that was washed with twice with hexane and dried under vacuum to provide 4-amino-2,5- dichloro-6-methoxycarbonylpyrimidine (15.0 g, 82 %). 1H nmr (400 MHz, d6-DMSO) deltaH 8.57 (1H, br s), 7.94 (1H, br s), 3.88 (3H, s) ppm.
With the rapid development of chemical substances, we look forward to future research findings about 89284-85-5.
Reference:
Patent; SYNGENTA LIMITED; SYNGENTA PARTICIPATIONS AG; WHITTINGHAM, William, Guy; WINN, Caroline, Louise; GLITHRO, Harry; BOUSSEMGHOUNE, Mohamed, Abdelouahab; ASPINALL, Mary, Bernadette; WO2010/92339; (2010); A1;,
Pyrimidine | C4H4N2 – PubChem,
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