Strekowski, Lucjan’s team published research in Journal of Organic Chemistry in 1991-09-13 | CAS: 84755-30-6

Journal of Organic Chemistry published new progress about Bromination, regioselective. 84755-30-6 belongs to class pyrimidines, name is 4-Methyl-2-(methylthio)pyrimidine-5-carbaldehyde, and the molecular formula is C7H8N2OS, Related Products of pyrimidines.

Strekowski, Lucjan published the artcileHighly regioselective bromination reactions of polymethylpyrimidines, Related Products of pyrimidines, the main research area is methylpyrimidine regioselective bromination; bσomomethylpyrimidine.

Methylpyrimidines I (R, R1 = H, Me; R2 = H, SMe) are brominated at C(5)-Me with NBS in CCl4 and at C4(6)-Me with Br2 in HOAc to give the bromomethyl derivatives in a high yield. The remaining Me group(s) can also be brominated with high regioselectivity. The 2-methylthio substituent is not oxidized under these conditions.

Journal of Organic Chemistry published new progress about Bromination, regioselective. 84755-30-6 belongs to class pyrimidines, name is 4-Methyl-2-(methylthio)pyrimidine-5-carbaldehyde, and the molecular formula is C7H8N2OS, Related Products of pyrimidines.

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia