Sulkowska, Anna published the artcileInteractions between pyrimidine bases derivatives and serum albumin in the presence of urea, Application of 3-Methylpyrimidine-2,4(1H,3H)-dione, the publication is Colloids and Surfaces, A: Physicochemical and Engineering Aspects (1999), 158(1-2), 151-156, database is CAplus.
A study of complex formation between pyrimidine base derivatives and serum albumin should allow us to determine the specificity of interactions of the pyrimidine derivatives with proteins. The role of the secondary and tertiary structure of serum albumin on the binding of the protein is also under investigation. The possible importance of the interactions between aliphatic residues of pyrimidine bases derivatives and serum albumin is discussed with respect to the problem of specific protein-nucleic acid interactions. The results suggest a release of ligands from their binding sites on the denatured polypeptide chain. The importance of hydrophobic interactions of the C5 Me group with hydrophobic grooves of protein in the presence of urea is suggested.
Colloids and Surfaces, A: Physicochemical and Engineering Aspects published new progress about 608-34-4. 608-34-4 belongs to pyrimidines, auxiliary class Pyrimidine,Amide, name is 3-Methylpyrimidine-2,4(1H,3H)-dione, and the molecular formula is C8H6KNO4S, Application of 3-Methylpyrimidine-2,4(1H,3H)-dione.
Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/Pyrimidine,
Pyrimidine – Wikipedia