Unprecedented Allenylidene Transfer from Chromium to Tungsten was written by Szesni, Normen;Drexler, Matthias;Fischer, Helmut. And the article was included in Organometallics in 2006.Quality Control of 2-Ethynylpyrimidine This article mentions the following:
Pyrimidylallenylidene complexes 1 ([(CO)5M:C:C:C(NC3H3NEt)]; M = Cr (a), W (b)) were prepared in a 1-pot procedure from readily available 2-ethynylpyrimidine, BuLi, [(CO)5M(THF)], and triethyloxonium tetrafluoroborate. In addition to 1a,b, the homobinuclear allenylidene complexes 2a,b ([(CO)5M:C:C:C(NC3H3NEt)M(CO)5]; M = Cr, W) were formed. In 2a,b the 2nd (CO)5M moiety is attached to the non-alkylated N atom of the pyrimidyl ring. Treatment of the Cr complex 1a with an excess of [(CO)5W(THF)] afforded the W allenylidene complex 2b by transmetalation of the allenylidene ligand and addition of (CO)5W. The allenylidene ligands of other Cr allenylidene complexes [(CO)5Cr:C:C:C(R1)R2] could likewise be transferred to W. In contrast, the reverse transmetalation from W to Cr could not be achieved. DFT calculations indicate that the reaction proceeds by an associative rather than a dissociative pathway. The initiating reaction step is coordination of a (CO)5W fragment to the Cα-Cβ bond of the allenylidene ligand. In the experiment, the researchers used many compounds, for example, 2-Ethynylpyrimidine (cas: 37972-24-0Quality Control of 2-Ethynylpyrimidine).
2-Ethynylpyrimidine (cas: 37972-24-0) belongs to pyrimidine derivatives. The aromatic compound pyrimidine, and its derivatives, are ubiquitous in nature. They are found in nucleic acids, vitamins, amino acids, antibiotics, alkaloids, and a variety of toxins. Pyrimidine derivatives have been used in a wide variety of pharmaceuticals including general anesthetics, anti-epilepsy medication, anti-malaria medication, drugs for treating high blood pressure, and HIV medication.Quality Control of 2-Ethynylpyrimidine
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia