Tag: 100-200

In 2017,Xiang, Yepeng; Zhao, Yongbiao; Xu, Nan; Gong, Shaolong; Ni, Fan; Wu, Kailong; Luo, Jiajia; Xie, Guohua; Lu, Zheng-Hong; Yang, Chuluo published 《Halogen-induced internal heavy-atom effect shortening the emissive lifetime and improving the fluorescence efficiency of thermally activated delayed fluorescence emitters》.Journal of Materials Chemistry C: Materials for Optical and Electronic Devices published the findings.Synthetic Route of C4HCl3N2 The information in the text is summarized as follows:

Halogenation of an electron acceptor in TADF emitters is presented as a feasible strategy for shortening the DF lifetimes of TADF emitters without sacrificing their photoluminescence quantum yields. A greenish-yellow device based on the chloride-substituted emitter (ClPPM) achieves a high external quantum efficiency of 22.2% and an ultra-slow efficiency roll-off of 12.3% at a practical luminance of 1000 cd m-2, which is comparable to the state-of-the-art device performance for green-to-yellow TADF OLEDs at the practical luminance. The results came from multiple reactions, including the reaction of 2,4,6-Trichloropyrimidine(cas: 3764-01-0Synthetic Route of C4HCl3N2)

2,4,6-Trichloropyrimidine(cas: 3764-01-0) is a member of organic chlorides. Organic chloride content in crude oil can be detected through specialized laboratory analysis. Care and attention are essential while sampling and testing.Synthetic Route of C4HCl3N2

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Cheng, Cong; Jiang, Yongshi; Wang, Haonan; Lou, Weiwei; Zhu, Yunhui; Deng, Chao; Wang, Dan; Tsuboi, Taiju; Li, Guijie; Zhang, Qisheng published their research in Journal of Materials Chemistry C: Materials for Optical and Electronic Devices in 2021. The article was titled 《Efficient and stable deep blue thermally activated delayed fluorescent molecules based on a bipyridine acceptor core》.HPLC of Formula: 3764-01-0 The article contains the following contents:

High efficiency and low cost organic light-emitting diodes (OLEDs) employing thermally activated delayed fluorescent (TADF) materials have attracted great attention. However, combining high quantum efficiency and stability is still challenging for deep blue TADF OLEDs. Here, we report a type of novel blue TADF emitter consisting of a bipyridine weak acceptor and four carbazole donors. These D-A-type emitters exhibit a high fluorescence rate of 9.8 x 107 s-1 and a small ΔEST of 0.08 eV owing to the energy approach of the frontier orbitals on the isolated D/A segments and adequate overlap of the frontier orbitals in the D-A systems. The organic light-emitting diodes containing these emitters offer deep blue emission with a half-width of 58 nm. High external quantum efficiencies of 15.3% and 18.7% are achieved in devices with emission maxima at 459 nm and 471 nm, resp. In comparison to the structurally analogous TADF emitters with a π-bridge between the donor and acceptor moieties, the bipyridine/carbazole derivatives with a compact “”donors-surrounding-acceptor”” structure exhibit superior stability in both photoluminescence and electroluminescence. The experimental process involved the reaction of 2,4,6-Trichloropyrimidine(cas: 3764-01-0HPLC of Formula: 3764-01-0)

2,4,6-Trichloropyrimidine(cas: 3764-01-0) is a member of organic chlorides. Organic chloride content in crude oil can be detected through specialized laboratory analysis. Care and attention are essential while sampling and testing.HPLC of Formula: 3764-01-0

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

The author of 《Underlying mechanism of CO2 adsorption onto conjugated azacyclo-copolymers: N-doped adsorbents capture CO2 chiefly through acid-base interaction?》 were Qi, Shi-Chao; Wu, Ju-Kang; Lu, Jie; Yu, Guo-Xing; Zhu, Rong-Rong; Liu, Yu; Liu, Xiao-Qin; Sun, Lin-Bing. And the article was published in Journal of Materials Chemistry A: Materials for Energy and Sustainability in 2019. COA of Formula: C4HCl3N2 The author mentioned the following in the article:

The empiricism that extrinsic or doped materials universally perform much better than their intrinsic counterparts has been verified to be feasible in the adsorptive CO2 capture. Thus, a variety of N-doped solid adsorbents are well-engineered to adsorb CO2. However, the true nature of the N-doped sites in the aggregation state and the underlying mechanism of CO2 adsorption therein are difficult to determine In the present study, four well-defined azacyclo copolymers with peculiar textural characteristics, uniformly arrays and tunably effective N-doped sites were fabricated to exptl. determine the precise relation between adsorbed CO2 mols. and the N-doped sites incorporated into an adsorbent. With multifaceted quantum chem. computations, induction forces were proven to account for the improved CO2 adsorption on the N-doped sites instead of the conventionally assumed generalized acid-base interaction. The neg. electrostatic potentials were demonstrated to be the real cause for improving the CO2 adsorption and a robust indicator for the effectiveness of the N-doped sites. Besides, a precise linear function is proposed to quant. describe this subject-object relationship for the first time. In the experimental materials used by the author, we found 2,4,6-Trichloropyrimidine(cas: 3764-01-0COA of Formula: C4HCl3N2)

2,4,6-Trichloropyrimidine(cas: 3764-01-0) is a member of organic chlorides. Organic chloride content in crude oil can be detected through specialized laboratory analysis. Care and attention are essential while sampling and testing.COA of Formula: C4HCl3N2

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

In 1952,Bollettino Scientifico della Facolta di Chimica Industriale di Bologna included an article by Andrisano, R.; Modena, G.. Category: pyrimidines. The article was titled 《Ultraviolet spectroscopic characteristics at different pH of 5-nitro-2X-substituted pyrimidines》. The information in the text is summarized as follows:

cf. C.A. 46, 9422c. The wave length of maximum absorption, λ, and the extinction coefficient of compounds of the type 5-nitro-2X-pyrimidine, in which X is Me, Ph, furyl, OH, OMe, SH, SMe, NH2, or Cl, were determined in 0.1 N HCl (pH 1), H2O (pH 7), and 0.1 N NaOH (pH 15), to discover if the NO2 group in position 5 would alter results previously found for mono-substituted compounds of the same type. In general the λ is fairly constant at pH 1-7, with the exception of X = CH3, when it jumps from 3065 to 3505 A. The compounds measured are classified as follows: symmetrical when X = NH2, quasisymmetrical when X = OH or SCH3, nonsymmetrical for the other 6 derivatives measured. In addition to this study using 2-Methoxy-5-nitropyrimidine, there are many other studies that have used 2-Methoxy-5-nitropyrimidine(cas: 14001-69-5Category: pyrimidines) was used in this study.

2-Methoxy-5-nitropyrimidine(cas: 14001-69-5) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.Category: pyrimidines

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Synthetic Route of C8H10N2O2On October 31, 1994 ,《The crafting of uracils with enhanced stacking potential》 appeared in Proceedings – Indian Academy of Sciences, Chemical Sciences. The author of the article were Ranganathan, Subramania; Kundu, Dinabandhu; Mehrotra, Sanjiv. The article conveys some information:

Uracils having enhanced stacking profile are of interest from diverse vantages ranging from the chem. simulation of transcription to the design of novel antiviral agents. This objective has been realized by synthetic strategies leading to uracils having, inter alia, pseudo aromatic and hydrophobic rings crafted to the 5-6 location and ionophore and hydrophobic chains affixed at the C-5 and nitrogen atoms. Endeavors to prepare a 5-2′ uracil-pyrimidine composite have led to novel uracil arising from 2-O → =CH(COOR)2 transformation and a tethered malonic acid pyrimidine complex. The results came from multiple reactions, including the reaction of Ethyl 2-(pyrimidin-2-yl)acetate(cas: 63155-11-3Synthetic Route of C8H10N2O2)

Ethyl 2-(pyrimidin-2-yl)acetate(cas: 63155-11-3) is a member of pyrimidine. Pyrimidine derivatives are an important class of N-heterocycles. They are well-known for their wide spectrum of promising biological activities such as antitumors, bactericidals, and fungicidal.Synthetic Route of C8H10N2O2

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

In 2017,Davodian, Tayebeh; Ranjbar-Karimi, Reza; Mehrabi, Hossein published 《Synthesis of diheteroaryl sulfides via chemoselective reaction of 4,6-diaminopyrimidine-2(1H)-thione with haloheteroaryl compounds》.Chemistry of Heterocyclic Compounds (New York, NY, United States) published the findings.Recommanded Product: 3764-01-0 The information in the text is summarized as follows:

A series of substituted diheteroaryl sulfides was synthesized by the reaction of 4,6-diaminopyrimidine-2(1H)-thione with fluoro- and chloroheteroarom. compounds in the presence of Na2CO3 in acetonitrile under reflux conditions. The study indicated that 4,6-diaminopyrimidine-2(1H)-thione reacts with fluoro- and chloroheteroarom. compounds chemoselectively as S- rather than N-nucleophile. The structures of the synthesized compounds were confirmed by IR, 1H, 19F, and 13C NMR spectroscopy, as well as elemental anal. and X-ray structural anal. The experimental process involved the reaction of 2,4,6-Trichloropyrimidine(cas: 3764-01-0Recommanded Product: 3764-01-0)

2,4,6-Trichloropyrimidine(cas: 3764-01-0) is a member of organic chlorides. Organic chloride content in crude oil can be detected through specialized laboratory analysis. Care and attention are essential while sampling and testing.Recommanded Product: 3764-01-0

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

In 2015,Esmaeilpour, Mohsen; Javidi, Jaber published 《Magnetically-recoverable Schiff Base Complex of Pd (II) Immobilized on Fe3O4@SiO2 Nanoparticles: An Efficient Catalyst for Mizoroki-Heck and Suzuki-Miyaura Coupling Reactions》.Journal of the Chinese Chemical Society (Weinheim, Germany) published the findings.Name: 2,4,6-Trichloropyrimidine The information in the text is summarized as follows:

The activity of Pd(II)-Schiff base complex mols. grafted on the surface of Fe3O4@SiO2 particles were investigated in the palladium-catalyzed coupling reactions of aryl halides with alkenes (Mizoroki-Heck reaction) and phenylboronic acids (Suzuki-Miyaura reaction) in the absence of phosphorous ligands. This method shows notable advantages such as heterogeneous nature of the catalyst, excellent yields, short reaction times, easy preparation, simplicity of operation, and cleaner reaction profiles. The catalyst can be separated from the reaction mixture by applying a permanent magnet externally and can be reused for several times without significant loss of activity. The amount of palladium leaching has been determined by ICP anal. The results came from multiple reactions, including the reaction of 2,4,6-Trichloropyrimidine(cas: 3764-01-0Name: 2,4,6-Trichloropyrimidine)

2,4,6-Trichloropyrimidine(cas: 3764-01-0) is a member of organic chlorides. Organic chloride content in crude oil can be detected through specialized laboratory analysis. Care and attention are essential while sampling and testing.Name: 2,4,6-Trichloropyrimidine

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

In 2015,Varalakshmi, Mavallur; Srinivasulu, Doddaga; Kotakadi, Venkata S. published 《Nano-BF3.SiO2 Catalyst-Promoted Michaelis-Arbuzov Reaction: Solvent-Free Synthesis and Antimicrobial Evaluation》.Phosphorus, Sulfur and Silicon and the Related Elements published the findings.HPLC of Formula: 3764-01-0 The information in the text is summarized as follows:

A simple, convenient synthetic route for the synthesis of novel dialkyl heteroaryl phosphonates by a reusable and green nano-BF3. SiO2 solid catalyst under solvent-free conditions through Michaelis-Arbuzov reaction with high yields is presented. All the newly synthesized compounds were characterized by spectral data and screened for their antimicrobial activity. Some of the compounds exhibited potent antibacterial activity against all the tested pathogens, and warrant further investigation. After reading the article, we found that the author used 2,4,6-Trichloropyrimidine(cas: 3764-01-0HPLC of Formula: 3764-01-0)

2,4,6-Trichloropyrimidine(cas: 3764-01-0) is a member of organic chlorides. Organic chloride content in crude oil can be detected through specialized laboratory analysis. Care and attention are essential while sampling and testing.HPLC of Formula: 3764-01-0

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

The author of 《Repurposing strategies on pyridazinone-based series by pharmacophore- and structure-driven screening》 were Floresta, Giuseppe; Crocetti, Letizia; Giovannoni, Maria Paola; Biagini, Pierfrancesco; Cilibrizzi, Agostino. And the article was published in Journal of Enzyme Inhibition and Medicinal Chemistry in 2020. COA of Formula: C11H8N2O The author mentioned the following in the article:

We report here in silico repurposing studies on 52 new pyridazinone-based small-mols. through inverse virtual screening (iVS) methodologies. These analogs were originally designed as formyl peptide receptor (FPR) ligands. As it is sometimes the case in drug discovery programs, subsequent biol. screening demonstrated the inefficacy of the mols. in binding FPRs, failing in the identification of new hits. Through a focussed drug-repurposing approach we have defined a variety of potential targets that are suitable to interact with this library of pyridazinone-based analogs. A two-step approach has been conducted for computational anal. Specifically, the mols. were initially processed through a pharmacophore-based screening. Secondly, the resulting features of binding were investigated by docking studies and following mol. dynamic simulations, in order to univocally confirm “”pyridazinone-based ligand-target protein”” interactions. Our findings propose aspartate aminotransferase as the most favorable repurposed target for this small-mol. series, worth of addnl. medicinal chem. investigations in the field. The results came from multiple reactions, including the reaction of 3-(Pyrimidin-5-yl)benzaldehyde(cas: 640769-70-6COA of Formula: C11H8N2O)

3-(Pyrimidin-5-yl)benzaldehyde(cas: 640769-70-6) belongs to pyrimidine. Pyrimidine nucleotide derivatives have a wide range of biological applications. For example, pyrimidine derivatives are useful in DNA repair studies involving cancer and epigenetics. COA of Formula: C11H8N2O

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

In 1970,Journal of the Chemical Society [Section] C: Organic included an article by Brown, Desmond J.; Sugimoto, T.. Application of 30561-07-0. The article was titled 《Aza analogs of pteridine. II. Novel use of silver oxide in transetherification of alkoxy-1,2,4,6,8-pentaazanaphthalenes, alkoxynitropyrimidines, and related systems》. The information in the text is summarized as follows:

Alkoxy derivatives of 1,2,4,6,8-pentaazanaphthalene (pyrimido[5,4-e]-as-triazine) (I) undergo transetherification when treated with boiling alcs. in the presence of silver oxide. Appropriate methoxy compounds give 5-ethoxy-3-methyl-, 5-propoxy-3-methyl-, and (more slowly) 5-isopropoxy-3-methyl-pentaazanaphthalene; also 5,7-diethoxy-, 5,7-dipropoxy-, 5,7-diisopropoxy-, 5,7-diethoxy-3-methyl-, and 5-ethoxy-3,7-di-methylpentaazanaphthalene. Synthetic routes to the methoxy substrates and to one of the products are reported; other structures are confirmed by uv and 1H NMR spectra. 4-Methoxypteridine undergoes transetherification similarly but simple alkoxypyrimidines and alkoxypyridines are resistant. However, the more highly activated 2-methoxy-5-nitro-, 4-methoxy-5-nitro-, and 2,4-dimethoxy-5-nitropyrimidine easily give their resp. propoxy homologs, and so does 2-methoxy-3,5-dinitropyridine. In contrast, 2,4-dimethoxy-6-methyl-5-nitropyrimidine gives only its 4-methoxy-2-propoxy homolog, and both 4,6-dimethoxy-5-nitro- and 4-methoxy-2,6-dimethyl-5-nitropyrimidine remain unchanged. The classical transetherification agent, ethanolic EtONa, reacts with 5,7-dimethoxypentaazanaphthalene to give the 7-ethoxy-5-hydroxy analog. This was identified by spectral comparison with its 5-hydroxy-7-methoxy homolog, itself synthesized by 5,6-addition of methanethiol to 7-methoxy-pentaazanaphthalene followed by dehydrogenation and selective hydrolysis. In the part of experimental materials, we found many familiar compounds, such as 2,4-Dimethoxy-5-nitropyrimidine(cas: 30561-07-0Application of 30561-07-0)

2,4-Dimethoxy-5-nitropyrimidine(cas: 30561-07-0) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.Application of 30561-07-0

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia