Application of 799557-86-1, Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. 799557-86-1, Name is 5-Bromo-2-(trifluoromethyl)pyrimidine, SMILES is BrC1=CN=C(N=C1)C(F)(F)F, belongs to pyrimidines compound. In a article, author is Elattar, Khaled M., introduce new discover of the category.
Heterocyclic steroids: Synthetic routes and biological characteristics of steroidal fused bicyclic pyrimidines
Natural steroids are characterized as a vital class of compounds, a type of secondary metabolites and components of cell membranes that widely accessible in plants or animals displayed significant pharmacological and varied biological properties. The present study aims to highlight the conveyed researches of synthetic routes adopted to obtain the various structures of steroidal fused bicyclic pyrimidines with substantial biological and pharmaceutical importance. The topic was discussed in light of the synthesis of fused [6 + 5] bicyclic systems, fused [6 + 6] bicyclic systems, binary heterocycles, and biological applications. In detail, the various synthetic strategies for the construction of steroids fused to bicyclic pyrazolopyrimidines, thiazolopyrimidines, triazolopyrimidines, pyridopyrimidines, pyranopyrimidines, and binary pyrimidines were discussed. Heterocyclic steroids of this class of compounds demonstrated potent anticancer, anti-proliferative, anti-neuro-inflammatory, anti-inflammatory, and anti-ulcer activities. It was perceived that the synthetic steroids of such bicyclic pyrimidine scaffolds are fused into the steroid basic skeleton is essential for the potent bioactivities.
Application of 799557-86-1, The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 799557-86-1 is helpful to your research.
Reference:
Pyrimidine | C4H4N2 – PubChem,
,Pyrimidine – Wikipedia