In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 1215787-31-7, name is 6-Bromo-4-chloropyrido[2,3-d]pyrimidine, the common compound, a new synthetic route is introduced below. SDS of cas: 1215787-31-7
General procedure: To a solution of compound 4 (2.43 g, 0.01 mol) in 25 mL dioxane was added 1-(2,6-Dichloro-3-fluorophenyl)ethan-1-amine (3.12 g, 0.015 mol), and then the reaction mixture was stirred at room temperature overnight. After that, the mixture was poured into 150 mL H2O, and then the resulting precipitate was filtered, washed with 50% ethanol, and dried overnight under vacuum to give 5a as white solid (3.58 g, yield, 86%).
The synthetic route of 1215787-31-7 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Hou, Ju; Wan, Shanhe; Wang, Guangfa; Zhang, Tingting; Li, Zhonghuang; Tian, Yuanxin; Yu, Yonghuan; Wu, Xiaoyun; Zhang, Jiajie; European Journal of Medicinal Chemistry; vol. 118; (2016); p. 276 – 289;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia