Synthetic Route of 13223-43-3, Adding some certain compound to certain chemical reactions, such as: 13223-43-3, name is 5,7-Dimethoxy-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine,molecular formula is C7H9N5O2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 13223-43-3.
General procedure: The compound 4a (6 g, 0.03 mol), catalytic amount of DMSO and3,5-lutidine (9.6 g, 0.09 mol) were dissolved in MeCN (15 mL), and then 7c (10.3 g, 0.03 mol) was addedslowly with stirring at 35 C and keeping for 1 h. The reaction system was heated to 45 C and kept thatuntil the complete conversion monitoring by HPLC. Then the resultant mixture was slowly added into10% sulfuric acid aqueous solution (100 mL). After filtering, the residue was purified by recrystallizingfrom MeCN to afford white solid, yield 13.5 g (89.6%);
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 13223-43-3, 5,7-Dimethoxy-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Ma, Yi-Chao; Yu, Ying-Hui; Hou, Guang-Feng; Huang, Ji-Han; Gao, Jin-Sheng; Heterocycles; vol. 92; 5; (2016); p. 829 – 843;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia