Related Products of 14394-70-8, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 14394-70-8, name is 2-Chloro-5-methylpyrimidin-4-amine. This compound has unique chemical properties. The synthetic route is as follows.
[0426] A mixture of 2-chloro-5-methyl-pyrimidin-4-ylamine (0.71 g, 4.9 nimol), intermediate 74 (1.25 g, 5.9 mmol), Pd2(dba)3 (0.45 g, 0.49 mmol), Xantphos (0.57 g, 0.98 mmol) and cesium carbonate (4.8 g, 14.7 mmol) were suspended in dioxane (40 mL) refluxed for 18 h. The reaction mixture was then cooled to room temperature, filtered and solvents evaporated. Resulting residue was purified by flash chromatography on silica gel to afford title compound as white solids (0.44, 32%).
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 14394-70-8, 2-Chloro-5-methylpyrimidin-4-amine.
Reference:
Patent; TARGEGEN, INC.; WO2007/53452; (2007); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia