Reference of 769-42-6, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.769-42-6, name is 1,3-Dimethylbarbituric acid, molecular formula is C6H8N2O3, molecular weight is 156.1393, as common compound, the synthetic route is as follows.
To a solution of 1,3-dimethylbarbituric acid (3.90 grams, 25.0 mmol) in 100 mL hot H2O was added a solution of benzaldehyde (2.65 grams, 25.0 mmol) in EtOH (20 mL). The resultant mixture was stirred vigorously while heating at reflux. After 5 hours, the mixture was allowed to cool to room temperature, and the precipitate was collected via filtration, washing with additional water. After drying overnight, this provided 5-benzylidene-l,3-dimethylpyrimidine-2,4,6-trione (5.90 grams, 97% yield) as a pale yellow solid.
Statistics shows that 769-42-6 is playing an increasingly important role. we look forward to future research findings about 1,3-Dimethylbarbituric acid.
Reference:
Patent; 3M INNOVATIVE PROPERTIES COMPANY; MOSER, William H.; TOWNSEND, Erik M.; THOMPSON, Zachary J.; CARUSO DAILEY, Mary M.; KROPP, Michael A.; (46 pag.)WO2019/152187; (2019); A1;,
Pyrimidine | C4H4N2 – PubChem,
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