Application of 13754-19-3, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 13754-19-3, name is Pyrimidine-4,5-diamine. A new synthetic method of this compound is introduced below.
A mixture OF 4, 5-DIAMINOPYRIMIDINE (1.0 g, 9.1 MMOL), N-(5-butoxycarbonyl)-4- piperidone (3.0 g, 15 mmol) and sodium triacetoxyborohydride (1.2 g, 5.6 mmol) in dichloroethane (60 mL) was stirred at room temperature for 3 d. The reaction was partitioned between chloroform (200 mL) and 3N sodium hydroxide (30 ML). After drying over magnesium sulfate, the organic phase was concentrated to give the title compound as a tan gum. MS 294 (M+1)
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,13754-19-3, its application will become more common.
Reference:
Patent; MERCK & CO., INC.; WO2004/92166; (2004); A2;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia