The origin of a common compound about 19646-07-2

Statistics shows that 19646-07-2 is playing an increasingly important role. we look forward to future research findings about 2,4-Dichloro-5-methoxypyrimidine.

Electric Literature of 19646-07-2, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.19646-07-2, name is 2,4-Dichloro-5-methoxypyrimidine, molecular formula is C5H4Cl2N2O, molecular weight is 179, as common compound, the synthetic route is as follows.

2, 4-dichloro-5-methoxy-pyrimidine (100g) is dissolved in methanol, the reaction of ammonia gas at room temperature 24 hours. Reaction solution to dryness under reduced pressure, obtaining white solid, by adding petroleum ether/ethyl acetate (the 10 […] 1) beating 3-5 time, suction filtration, the white solid obtained 61 g.

Statistics shows that 19646-07-2 is playing an increasingly important role. we look forward to future research findings about 2,4-Dichloro-5-methoxypyrimidine.

Reference:
Patent; Shanghai Pharmaceutical Co., Ltd. Allist; Luo, Huibing; Wu, Yong; Zhou, Huayong; (67 pag.)CN105218561; (2016); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia