The origin of a common compound about 2-Chloro-4,6-diphenylpyrimidine

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 2915-16-4, 2-Chloro-4,6-diphenylpyrimidine, other downstream synthetic routes, hurry up and to see.

Related Products of 2915-16-4, Adding some certain compound to certain chemical reactions, such as: 2915-16-4, name is 2-Chloro-4,6-diphenylpyrimidine,molecular formula is C16H11ClN2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 2915-16-4.

Shenzhen’s gre-syn chemical technology (http://www.gre-syn.com/) in a nitrogen environment, 2-chloro-4,6-diphenylpyrimidine (20 g, 75.0 mmol) was dissolved in tetrahydrofuran (THF) 0.3 L , here it was stirred into the compound I-7 (38.1 g, 75.0 mmol) and tetrakis (triphenylphosphine) palladium (0.87 g, 0.75 mmol). Into the potassuim carbonate (25.9 g, 188 mmol) in saturated water it was heated to reflux at 80 for 15 hours. After the reaction was completed, the reaction solution into water and extracted with dichloromethane (DCM) and then water was removed with anhydrous MgSO4, filter and was concentrated under reduced pressure. The obtained residue was purified by flash column chromatography to give the Compound 9 (43.2 g, 94%).

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 2915-16-4, 2-Chloro-4,6-diphenylpyrimidine, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; CHEIL INDUSTRIES INC.; HAN ILL, LEE; SU JIN, HAN; YOUNG KWON, KIM; EUN SUN, YU; HO KUK, JUNG; (66 pag.)KR2015/117173; (2015); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia