Electric Literature of 22536-65-8, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 22536-65-8, name is 2-Chloro-5-methoxypyrimidine. This compound has unique chemical properties. The synthetic route is as follows.
(A)A mixture of 2-chloro-5-methoxypyrimidine (10 g, 69.44 mmol, 1 eq) MeOH-CH3CN 4:1 (160 ml -40ml), TEA (20 ml) and Pd(dppf)Cl2 DCM (6 g, 7.34 mmol, 0.1 eq) in an autoclave, was stirred at 100C for18 h under CO gas atmosphere. The RM was cooled to RT, filtered through celite, washed with MeOH(100 ml), and the filtrate was concentrated. The residue upon purification by CC (silica gel; EtOAc – PE;3:7) afforded methyl 5-methoxypyrim idine-2-carboxylate (6 g, 52%).
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 22536-65-8, 2-Chloro-5-methoxypyrimidine.
Reference:
Patent; GRUeNENTHAL GMBH; SCHUNK, Stefan; REICH, Melanie; JAKOB, Florian; DAMANN, Nils; HAURAND, Michael; KLESS, Achim; ROGERS, Marc; SUTTON, Kathy; WO2015/158427; (2015); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia