Adding a certain compound to certain chemical reactions, such as: 18740-39-1, 2,4-Dichlorothieno[2,3-d]pyrimidine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 18740-39-1, blongs to pyrimidines compound. Computed Properties of C6H2Cl2N2S
Under a nitrogen stream 2,4-dichlorothieno [2,3-d] pyrimidine (4.2 g, 20.5 mmol), phenylboronic acid (2.5 g,Pd (PPh3) 4 (1.2 g, 5 molpercent) and potassium carbonate (8.5 g, 61.5 mmol)Toluene / H 2 O / Ethanol (80 ml / 40 ml / 40 ml) was added thereto, and the mixture was stirred at 110 ° C for 4 hours.After completion of the reaction, the organic layer was separated using methylene chloride, and water was removed using MgSO4. Solvent in organic layerThe residue was purified by column chromatography to obtain the target compound TP-1 (3.0 g, 12.3 mmol, yield 60percent).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,18740-39-1, its application will become more common.
Reference:
Patent; Doosan Corporation; Kim, Hong Suk; Sim, Jae Uii; Kim, Tae Hyung; Lee, In Hyuk; La, Jong Gyu; Kim, Uhn Jin; Baek, Young Mi; (56 pag.)KR2015/36982; (2015); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia