Application of 5750-76-5, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 5750-76-5, name is 2,4,5-Trichloropyrimidine, molecular formula is C4HCl3N2, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
Take 9 (23.44 mmol) and DIPEA (4.5 g, 35.16 mmol) in 50 mL dioxane,8 (3.8 g, 23.44 mmol) was added slowly, warmed to 60 C,After 5 hours reaction, the reaction was completed, cooled, 400mL water was added,Precipitation yellow-white solid, suction filtration, drying,Obtained as a white solid, without purification directly to the next reaction.
According to the analysis of related databases, 5750-76-5, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Dalian Medical University; Ma Xiaodong; Ge Yang; Song Zhendong; Huang Shanshan; Wang Changyuan; Zhang Jianbin; Tang Zeyao; Liu Kexin; (22 pag.)CN106565782; (2017); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia