Electric Literature of 151266-23-8, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 151266-23-8, name is 3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine. This compound has unique chemical properties. The synthetic route is as follows.
3-iodo-lH-pyrazolo [3,4-d] pyrimidin-4-amine, respectively, in a 250 mL thick walled reaction flask(1.31 g, 5.0 mmol), (4-phenoxyphenyl) boronic acid (1.28 g, 6.0 mmol), potassium carbonate (1.73 g, 12.5 mmol), 1,4-dioxane (30 mL) and water (6 mL). Pd (dppf) Cl2 (300 mg, 0.41 mmol) was added under nitrogen and the reaction was sealed overnight at 140 C. After completion of the reaction, the reaction mixture was filtered and extracted with dichloromethane 3), washed with saturated brine (60 mL) and dried over anhydrous sodium sulfate. The solvent was distilled off under reduced pressure, and the residue was purified by silica gel column chromatography (dichloromethane / methanol (V / V) = 20/1) , 42%).20/1) to give a tint solid (635 mg, 42%
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 151266-23-8, 3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine.
Reference:
Patent; Guangdong HEC Pharmaceutical Co., Ltd; LIU, BING; BAI, SHUN; ZHANG, YINGJUN; ZHENG, CHANGCHUN; YANG, TIPING; ZHOU, YOUBAI; (33 pag.)CN105399756; (2016); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia