Synthetic Route of 3270-97-1, Adding some certain compound to certain chemical reactions, such as: 3270-97-1, name is 2,4-Diamino-6-methoxypyrimidine,molecular formula is C5H8N4O, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 3270-97-1.
EXAMPLE 3 Preparation of diethyl 6-methoxypyrimidine-2,4-dioxamate monohydrate: 2,4-Diamino-6-methoxypyrimidine (3.78 g) is dissolved in anhydrous pyridine (20 ml) and thereto is added dropwise ethyloxalyl chloride (9.83 g) under ice cooling, and the mixture is stirred at room temperature for one hour. To the reaction mixture is added water, and the mixture is extracted with ethyl acetate. The organic layer is washed with water and saturated aqueous sodium chloride, dried over anhydrous sodium sulfate and concentrated under reduced pressure. The resulting solid is recrystallized from water-ethanol to give title compound (8.8 g) having the following physical properties. m.p. 132-134 C. IR (KBr) nu: 3625, 3530, 3420, 3010, 1740, 1610, 1530, 1475, 1400, 1305, 1210, 1170, 1100, 1050, 1015, 970, 840 cm-1. NMR (DMSO-d6) delta: 11.30 (1H, s), 10.60 (1H, s), 7.03 (1H, s), 4.29 (4H, q), 3,87 (3H, s), 1.30 (3H, t), 1.25 (3H, t). Elementary analysis: Calcd.: C, 43.58; H, 5.06; N, 15.64 (%). Found: C, 43.75; H, 4.85; N, 15.89 (%).
According to the analysis of related databases, 3270-97-1, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Toyo Boseki Kabushiki Kaisha; US4729995; (1988); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia