Application of 35265-83-9, Adding some certain compound to certain chemical reactions, such as: 35265-83-9, name is 2,4-Dichloro-7-methylthieno[3,2-d]pyrimidine,molecular formula is C7H4Cl2N2S, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 35265-83-9.
Reference Example 35 2-Chloro-7-methyl-4-piperidinoaminothieno[3,2-d] pyrimidine In DMF (N,N-dimethylformamide) was dissolved 700 mg (3.4 mmol) of 2,4-dichloro-7-methylthieno[3,2-d] pyrimidine, and then a solution of 751 mg (7.5 mmol) of 1-aminopiperidine was added dropwise to the resulting solution under ice cooling over 5 minutes. The reaction solution was stirred at 0C. for one hour and then allowed to resume room temperature, followed by stirring for further one hour. After completion of the reaction, ice water was added to the reaction mixture, followed by extraction with ethyl acetate (50 ml*3). After the organic layer was washed successively with 1N hydrochloric acid, water and brine and dried over anhydrous sodium sulfate, the solvent was distilled off under reduced pressure. The residue was purified by silica gel chromatography (eluent: ethyl acetate-hexane= 1/8) to give 573 mg (yield: 59.4%) of the title compound. NMR (delta, CDCl3): 1.20-1.28 (1H, m), 1.76-1.91 (5H, m), 2.41 (3H, s), 2.44-2.49 (2H, m), 3.17-3.20 (2H, m), 6.46 (1H, s), 7.46 (1H, s)
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 35265-83-9, 2,4-Dichloro-7-methylthieno[3,2-d]pyrimidine, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; NAKASHIMA, YOSHIHARU; FUJITA, TAKASHI; HIZUKA, MICHIYO; IKAWA, HIROSHI; HIRUMA, TORU; US2001/6969; (2001); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia