Reference of 36082-50-5, Adding some certain compound to certain chemical reactions, such as: 36082-50-5, name is 5-Bromo-2,4-dichloropyrimidine,molecular formula is C4HBrCl2N2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 36082-50-5.
General procedure: Heteroaryl chloride (1.0 eq), the corresponding amino alcohol (1.1 eq) and triethylamine (1.5 eq), were dissolved in n-BuOH (1 mL). The resulting reaction mixture was degassed with argon and irradiated in a commercial microwave apparatus at 125 C (30 W) for 1 h. Upon completion the solvent was removed under reduced pressure. The residue was purified by flash column chromatography (methanol : dichloromethane; 1:9) to afford the title compound.
According to the analysis of related databases, 36082-50-5, the application of this compound in the production field has become more and more popular.
Reference:
Article; Gill, Daniel M.; Iveson, Matthew; Collins, Ian; Jones, Alan M.; Tetrahedron Letters; vol. 59; 3; (2018); p. 238 – 242;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia