Related Products of 39906-04-2 ,Some common heterocyclic compound, 39906-04-2, molecular formula is C5H5Cl2N3, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
To a mixture of 4,6-dichloro-2-methylpyrimidin-5amine(1 g, 5.62 mmol) and O-ethyl carbonisothiocyanatidate(0.66 ml., 5.62 mmol) was added toluene (2 mL) to wet thesolids completely. The mixture was placed on 1000 C. oil bathfor 1.5 hours, at which time, the mixture had seized to give asolid mass. The solids were cooled to ambient temperatureand triturated with ether, then the resulting solids were collectedby filtration to give ethyl 7-chloro-5-methylthiazolo[5,4-d]pyrimidin-2-ylcarbamate (1.08 g, 3.96 mmol, 70.5%yield).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 39906-04-2, 4,6-Dichloro-2-methylpyrimidin-5-amine, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; BRISTOL-MYERS SQUIBB COMPANY; COOK II, JAMES H; MCDONALD, IVAR M; KING, DALTON; OLSON, RICHARD E; WANG, NENGHUI; IWUAGWU, CHRISTIANA I; ZUSI, F.CHRISTOPHER; MACOR, JOHN E; (330 pag.)JP5714745; (2015); B2;,
Pyrimidine | C4H4N2 – PubChem,
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